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Ephesians Outline
Ephesians 4:18

18 Being 1adarkened in their understanding, alienated from the 2blife of God because of the 3cignorance which is in them, because of the 4dhardness of their heart;

181 When the mind of fallen people is filled with vanity, their understanding is darkened regarding the things of God. Thus, they are alienated, separated, from the life of God.